Cyld antibody
WebMar 2, 2024 · The CYLD protein has three cytoskeleton-associated proteinglycine-rich (CAP-Gly) domain, two proline-rich (PR) domain, and a USP domain, which primary removes K63 or M1 polyubiquitin chains from... WebWestern Blot: CYLD Antibody [NB100-78600] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/ Immunofluorescence: CYLD Antibody [NB100 …
Cyld antibody
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WebCylindromatosis (CYLD) is a deubiquitinase (DUB) enzyme that was initially characterized as a tumor suppressor of adnexal skin tumors in patients with CYLD syndrome. Later, it was also shown that the expression of functionally inactive mutated forms WebCYLD Antibodies . Target Information. CYLD is a 956 aa, cytoplasmic, deubiquitinating enzyme belonging to the ubiquitin carboxy-terminal hydrolases (UCH) family of proteins with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains, a proline rich region, a SH3 binding domain and a sequence homology to catalytic domain of ...
WebCYLD is identified as a tumor suppressor protein affecting the JNK signaling pathway. CYLD is a negative regulator of TRAF2 and NF-kappa-B signaling pathway and is also … WebJan 9, 2024 · cylindromatosis 1 Antibody (E-10) is an IgG2a κ mouse monoclonal cylindromatosis 1 antibody (also designated cylindromatosis 1 antibody or CYLD …
WebApr 10, 2024 · CYLD is a deubiquitinating enzyme that plays a crucial role in immunity and inflammation as a negative regulator of NF-κB transcription factor and JNK kinase signaling. Defects in either of these pathways contribute to the progression of numerous inflammatory and autoimmune disorders. Therefore, we set out to unravel molecular mechanisms that … WebMar 15, 2024 · Here, we show that low expression of CYLD is associated with inferior prognosis of diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) …
WebUbiquitin carboxyl-terminal hydrolase CYLD antibody; ubiquitin specific peptidase like 2 antibody; ubiquitin thioesterase CYLD antibody; Ubiquitin thiolesterase CYLD antibody; …
WebMeanwhile, inhibition of CYLD did not affect the quality of antibody. Thus, our data demonstrated that inactivation of CYLD could promote CHO cell proliferation, anti-apoptosis ability, and subsequent antibody production, suggesting that CYLD is a potential functional target for CHO cell engineering. can lupron cause weight gainWebImmunohistochemistry analysis of paraffin-embedded CYLD in human brain cancer tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with CYLD polyclonal antibody (Product # PA5-106325) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit. fixd account loginWebView Rabbit Polyclonal anti-CYLD Antibody (NBP2-92436). Validated Applications: WB, IHC, IHC-P. Validated Species: Human, Mouse, Rat. Sample size available. fix damaged coach handbagsWebCYLD Antibody quantity + Increase Quantity. Add to cart. Datasheet. Shipping Info. $65 Standard Overnight flat rate for as many products shipped within the United States. $35 Dry Ice Shipment fee may be required on some items. Note: Online orders only accepted for shipment within the USA. fix cut patio screenWebContact Creative Biolabs to Customize CYLD1 Antibody, which reacts with C. elegans (Caenorhabditis elegans). This product is a mouse antibody against CYLD1. It can be used for CYLD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. can lupus affect blood sugarWebMay 18, 2024 · Here, we demonstrate that the deubiquitinase Cyld prevents excessive interleukin 18 (IL-18) production in the colonic mucosa by deubiquitinating NLRP6. We show that deubiquitination inhibited the... fix damaged car rimsWebMar 11, 2016 · Cutaneous cylindroma is an adnexal tumour with apocrine differentiation. A predisposition to multiple cylindromas is seen in patients with Brooke–Spiegler syndrome, who carry germline mutations in the tumour suppressor gene CYLD.Previous studies of inherited cylindromas have highlighted the frequent presence of bi-allelic truncating … fix damaged files online