Flotillin function
WebImmunogen: Mouse Flotillin aa. 312-428 Application: Western blot (Routinely Tested), Immunofluorescence (Tested During Development) Target Molecular Weight: 48 kDa Concentration: 250 µg/ml RRID: AB_398139 Storage Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. Regulatory Status: RUO View All … WebFlotillin-1 and -2 ... At a Keystone Symposium on Lipid Rafts and Cell Function in 2006, a consensus was reached that the term ‘lipid rafts’ should be changed to ‘membrane rafts’ recognizing the role of raft proteins, and that caveolae should be considered a membrane raft. Another issue which was discussed at that meeting and that has ...
Flotillin function
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WebMay 26, 2014 · The ubiquitous and highly conserved flotillin proteins, flotillin-1 and flotillin-2, have been shown to be involved in various cellular processes such as cell adhesion, signal transduction through receptor tyrosine kinases as well as in cellular trafficking pathways. Due to the fact that flotillins are acylated and form hetero-oligomers, … WebFlotillin-1 is a protein that in humans is encoded by the FLOT1 gene. Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal …
WebMar 26, 2024 · Additional functions unique to flotillin-1 have been discovered recently. The membrane-binding of flotillins is regulated by S-palmitoylation and N-myristoylation, … WebApr 1, 2009 · Flotillin-1 and flotillin-2 co-assemble into plasma membrane microdomains that are involved in the endocytosis of molecules such as glycosyl phosphatidylinositol (GPI)-linked proteins. Previous studies suggest that budding of flotillin microdomains from the plasma membrane is a tightly regulated process.
WebNov 27, 2009 · These results imply that flotillins are conserved between plants and animals. The conserved subcellular localization suggests the possibility of conserved function(s). In this work, we employ a reverse genetics approach to investigate the role of the Medicago truncatula flotillin-like gene family (FLOTs) in symbiosis. Webby which to explore the structure and function of caveolae organelles. Interestingly, flotillin is a close homologue of ESA1 (epidermal surface antigen (33)), and together they define a new “flotillin family” of caveolae-associated integral membrane proteins (flotillin-1 and flotillin-2/ESA)) (31). However, the
WebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton [10] – [12], for signaling events [13], …
WebMay 24, 2016 · Flotillin-1 (Flot1, reggie-2) is a lipid raft-associated scaffolding protein that belongs to a family of proteins characterized by an evolutionarily conserved SPFH domain (Browman et al., 2007; Langhorst et al., 2008).Although flotillin-1 is ubiquitously expressed, it is known to be highly expressed in brain tissue, and has been shown to serve distinct … smart health contact numberWebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … hillsborough community college emt courseWebFeb 19, 2014 · For a review on flotillin functions in general, the reader is referred to two recent review articles [1,2]. The MAP kinase signaling cascade is the canonical … hillsborough college flWebApr 15, 2024 · Flotillin 1 and 2 structures and localization. a Representation of the main domains and residues in the flotillin 1 and 2 sequences. SPFH (stomatin, prohibitin, … hillsborough college baseballWebAug 9, 2005 · Reggie/flotillin proteins are considered to be components of lipid rafts and are commonly used as marker proteins for lipid microdomains. Yet almost a decade after their discovery, the function of reggies/ flotillins is still enigmatic. In this review we summarize the present state of knowledge on reggie/flotillin structure, localization and … smart health definitionWebDec 31, 2013 · Flotillin-1 and flotillin-2 are two homologous, membrane raft associated proteins. Although it has been reported that flotillins are involved in cell adhesion processes and play a role during breast cancer progression, thus making them interesting future therapeutic targets, their precise function has not been well elucidated. The present … smart health covid testingWeb8.2 Flotillins. Flotillin-1 and -2 (also called reggie-2 and -1, respectively) are ubiquitously expressed, evolutionary conserved peripherally membrane-associated proteins of approximately 48 kDa. Palmitoylation on cysteine 34 is essential for membrane association of flotillin-1 ( Morrow et al., 2002) and myristoylation of glycine 2 for that of ... smart health consulting project ماهو