WebAug 7, 2024 · Cre小鼠的简介与应用. 1. Cre-loxp系统及其应用介绍. Cre-loxp系统源于P1噬菌体的高效重组系统。. Cre (Causes recombination; Cyclization recombinase)是38KD的位 … WebCre-loxP重组系统是一种位点特异的基因重组技术,被广泛应用于特异位点的基因敲除、基因插入、基因翻转和基因易位,在真核生物和原核生物中均有广泛应用。 Cre 蛋白是一种重组酶,是causes recombination的缩写,于1981 年从 P1 噬菌体中被发现,属于 λInt 酶超基因 ...
基因工程鼠概述 - 简书
WebJan 21, 2024 · 先说 Xcr1^ {iCre} 老鼠。. 它指的是在老鼠的基因组中插入了一个连接有mCherry的Cre片段,该片段在XCr1启动子的控制之下,只会在cDC1细胞表达。. 表达 … WebAug 20, 2024 · Cre/loxP重组系统优势及问题. (1)高效性:Cre重组酶与具有loxP位点的DNA片段形成二聚体后,可提供足够的能力引发之后的DNA重组过程,重组过程简约高效;. (4)可由二型启动子启动表达:Cre重组酶的编码基因可由任何一种二型启动子驱动,由此保证Cre重组酶在 ... fitted sheet hospital bed
Glp1r-ires-Cre… Harvard Office of Technology Development
http://www.labmodel.cn/mod_product-view-p_id-4258.html Web006410 B6;129S6- Chat tm2(cre)Lowl /J ChAT-IRES-Cre knock-in mice express Cre recombinase in cholinergic neurons, without disrupting endogenous Chat expression. These mice may be useful in neurobiological research of motor function, learning and memory, Alzheimer's disease, and Down syndrome, as well as obesity and diabetes research. The ... Web016963 STOCK Slc17a6 tm2(cre)Lowl /J Vglut2-ires-Cre knock-in mice have Cre recombinase expression directed to excitatory glutamatergic neuron cell bodies, without … JAX Center for Addiction Biology. The JAX Center for Addiction Biology is an … EEO Statement. The Jackson Laboratory provides equal employment … The JAX Endowment for Diversity Initiatives aims to ensure that individuals across … MGI Workshops. If you would like to host an MGI workshop at your institution, contact … Legal information including technology transfer, audit, public disclosure, terms … fitted sheet full size dimensions